王玥，特聘研究员，博士生导师

电子邮件：y.wang@ecust.edu.cn

通讯地址：上海市徐汇区梅陇路130号，华东理工大学，200237

办公室：华东理工大学徐汇校区实验十三楼115室

研究方向：化学生物学，功能材料，材料工程

招生专业：化学生物学 （博士/硕士）

教育及工作经历：

2010.09-2014.06   天津大学                    生物工程专业        本科

2014.10-2016.10   澳大利亚昆士兰大学   生物与化学科学     研究型硕士

2017.01-2020.10   澳大利亚昆士兰大学   材料工程                博士

2020.12-2025.07   澳大利亚昆士兰大学   博士后，澳大利亚国立健康与医学研究理事会新兴领导力研究员

2025.07-至今       华东理工大学             特聘研究员

主持项目：

澳大利亚国立健康与医学研究理事会青年拔尖基金

澳大利亚研究理事会联合项目

研究成果：

主要面向生命健康与精准医疗，融合材料工程、生物技术与细胞分子生物学，聚焦于解决传统抗菌材料疗效不足及免疫细胞内mRNA转染效率低等核心问题，通过纳米材料理化特性的工程化设计调控生物相互作用，应用于无抗生素抗菌、免疫抗癌等疾病的诊疗场景。已发表论文34篇，H指数为20。

代表性论文：

1. Yue Wang, Yining Yao, Yue Zhang, Yingjie Yu, Jiangqi Luo, Matthew J. Sweet and Chengzhong Yu*, Macrophage Phenotype Matters in the Design of Advanced Gene Delivery Carriers, Advanced Materials,2024, 37, 2401504

2. Yue Wang, Hao Song, Chao Liu, Ye Zhang, Yueqi Kong, Jie Tang, Yannan Yang and Chengzhong Yu*, Confined growth of ZIF-8 in dendritic mesoporous organosilica nanoparticles as bioregulators for enhanced mRNA delivery in vivo, National Science Review, 2021, 8, nwaa268

3. Yue Wang and Chengzhong Yu*, Emerging concepts of nanobiotechnology in mRNA delivery, Angewandte Chemie,2020, 59, 23374-23385

4. Yue Wang, Jie Tang, Yannan Yang, Hao Song, Jianye Fu, Zhengying Gu and Chengzhong Yu*, Functional nanoparticles with a reducible tetrasulfide motif upregulate messenger RNA translation and enhance transfection in hard-to-transfect cells, Angewandte Chemie,2020, 59, 2695-2699

5. Yue Wang, Yannan Yang, Yiru Shi, Hao Song* and Chengzhong Yu*, Antibiotic-free antibacterial strategies enabled by nanomaterials: progress and perspectives, Advanced Materials, 2020, 32, 1904106 (inside front cover, ESI Highly Cited Papers)

6. Yue Wang, Hao Song, Yannan Yang, Yang Liu, Jie Tang and Chengzhong Yu*, Kinetically controlled dendritic mesoporous silica nanoparticles: from dahlia- to pomegranate-like structures by micelle filling, Chemistry of Materials, 2018, 30, 5770-5776

7. Yue Wang, Hao Song, Meihua Yu, Chun Xu, Yang Liu, Jie Tang, Yannan Yang and Chengzhong Yu*, Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance, Journal of Materials Chemistry B, 2018, 6, 4089-4095

8. Yue Wang, Yusilawati Ahmad Nor, Hao Song, Yannan Yang, Chun Xu, Meihua Yu and Chengzhong Yu*, Small-sized and large-pore dendritic mesoporous silica nanoparticles enhanced antimicrobial enzyme delivery, Journal of Materials Chemistry B, 2016, 4, 2646-2653

9. Jiangqi Luo#, Yue Wang#, Zan Dai#, Yiru Shi, Weixi Wu, Jingjing Qu, Yuening Zhong, Jianqiao Xian Chengzhong Yu* and Yannan Yang, Passivation‐Engineered Zinc Peroxide Nanoparticles as Th1‐Biased Adjuvant for Antitumor Immunity, Small,2025, 10.1002/Smll.202505250

10. He Xian, Yaping Song, Jingjing Qu, Yiru Shi, Yue Zhang, Weixi Wu, Minjun Kim, Yue Wang*, and Chengzhong Yu*, CaClOH modified silica nanoparticles for mRNA delivery, Nano Lett., 2025, 25 (16), 6365-6373 (IF: 9.6)

11. Qihui Kan, Yaping Song, Yining Yao, Jun Zhang, He Xian, Dan Cheng, Yue Wang*, Liang Mao*, Meiyan Wang, Chengzhong Yu*, A core-shell-structured zeolitic imidazolate framework@cationic antimicrobial agent templated silica nanocomposite for tackling antibiotic resistant bacteria infection, Aggregate, 2024, 5, e523

12. Yining Yao, Zilin Ye, Yue Zhang, Yue Wang*, Chengzhong Yu*, Quaternary Ammonium Compounds and Their Composites in Antimicrobial Applications. Adv. Mater. Interfaces, 2024, 2300946.

13. Yue Zhang, Yingjie Yu, Yannan Yang*, Yue Wang* and Chengzhong Yu*, Engineered silica nanoparticles for nucleic acid delivery,Small Methods, 2023, 2300812

14. Yue Zhang, He Xian, Ekaterina Strounina, Kimberley S. Gunther, Matthew J. Sweet, Chen Chen, Chengzhong Yu* and Yue Wang*, Mesoporous organosilica nanoparticles with tetrasulphide bond to enhance plasmid DNA delivery, Pharmaceutics, 2023, 15 (3), 1013

15. He Xian, Yue Zhang, Chengzhong Yu* and Yue Wang*, Nanobiotechnology enabled mRNA stabilization, Pharmaceutics, 2023, 15 (2), 620 (IF: 4.9)

16. Yue Zhang, Yue Wang,* Yaping Song, Jiangqi Luo, Yingjie Yu, and Chengzhong Yu*, Synthesis of mesoporous organosilica nanoparticles with a high tetrasulfide content and large pores, Microporous and Mesoporous Materials, 2022, 346, 112316

17. Yaping Song, Qiang Sun, Jiangqi Luo, Yueqi Kong, Bolin Pan, Jing Zhao, Yue Wang,* and Chengzhong Yu*, Cationic and Anionic Antimicrobial Agents Co-templated Mesostructured Silica Nanocomposites with a Spiky Nanotopology and Enhanced Performance, Nano-Micro Letters, 2022,14 (1), 1-11

18. Ye Zhang, Zhengying Gu, Yang Liu, Wenli Hu, Chao Liu, Weikang Shu, Yue Wang*, Chengzhong Yu*, Benzene-bridged organosilica modified mesoporous silica nanoparticles via an acid-catalysis approach, Langmuir,2021, 37, 8, 2780-2786

19. Jiangqi Luo, Yue Wang, Chengzhong Yu*, Yannan Yang*, Bimetallic Nanoadjuvants: A Next-Generation Platform for Cancer Vaccines, Trends in Pharmacological Sciences, 2025 (accepted, TIPS-D-25-00168R1)