张玉涛，特聘副研究员，硕士生导师
邮箱：zhangyutao@ecust.edu.cn
办公地址：上海市徐汇区梅陇路130号，华东理工大学，实验三楼435
招生专业：化学生物学
教育及工作经历：
2012.09 – 2016.06 华东理工大学 应用化学 本科
2016.09 – 2021.06 华东理工大学 应用化学 博士 （导师：郭志前 教授）
2021.06 – 2024.08 华东理工大学 博士后 （合作导师：朱为宏 院士）
2024.09 – 至今 华东理工大学 化学与分子工程学院 特聘副研究员
研究方向：
主要研究方向包括菁染料类术中导航探针与光激活化学发光探针
围绕术中导航应用开发系列胸导管、胆管、肾损伤、肿瘤实时传感近红外荧光探针；围绕光激活化学发光体系开发氧气浓度、活性氧、酶、以及血脑屏障超高灵敏度传感化学发光探针。已在 Angew. Chem. Int. Ed., Chem. Sci., Sci. China Chem.等期刊发表研究论文17篇。申请专利3项，授权1项。
主持科研/人才项目：
1、国家自然科学基金青年基金，在研
2、上海市“超级博士后”激励计划，结题
3、中国博士后科学基金第70批面上项目，结题
代表性论文：
(1) Li, J., Zhao, X., Zhang, Y.*, Lu, Y., Xue, H., Li, D., Liu, Q., Yan, C., Chi, W., Xiao, X., Zhu, W.-H., Guo, Z., A two-dimensional fluorescence and chemiluminescence orthogonal probe for discriminating and quantifying similar proteins. Chem. Sci. 2025, 16, 3228.
(2) Zhao, M., Lu Y., Zhang, Y.*, Xue H., Guo, Z.*, Ultra-High Signal-to-noise Ratio Near-Infrared Chemiluminescent Probe for in vivo Sensing Singlet Oxygen. Chin. Chem. Lett. 2025, 36, 110105.
(3) Zhao, Z., Zhang Y.*, Wu M., Yan C., and Guo Z.* A Reversible Dual-Channel Near-Infrared Flavonoid Probe for in Vivo Tracking Glutathione Dynamics in Living Mice. Chem. Biomed. Imaging 2023, 1, 620–627.
(4) Zhang, Y., Juan, L., Zhu, W.H., Guo, Z. Sequence-Activated Chemiluminescence Probes: Programmable Il-lumination for High-Contrast in Vivo Sensing and Imaging. Sci. China Chem. 2025, 68, 26.
(5) Zhang, Y., Yan, C., Wang, C., Guo, Z., Liu, X., Zhu, W. H. A Sequential Dual-Lock Strategy for Photoactivatable Chemiluminescent Probes Enabling Bright Duplex Optical Imaging. Angew. Chem. Int. Ed. 2020, 59, 9059.
(6) Zhang, Y., Yan, C., Zheng, Q., Jia, Q., Wang, Z., Shi, P., Guo, Z. Harnessing Hypoxia-Dependent Cyanine Photocages for In Vivo Precision Drug Release. Angew. Chem. Int. Ed. 2021, 60, 9553.
(7) Lu Y.#, Zhang, Y.#, Xia, W., Pu, R., Yan, C., Liu, W., Liu, X., Guo, Z., Zhu, W.H. A De Novo Zwitterionic Strategy of Ultra-stable Chemiluminescent Probes: Highly Selective Sensing Singlet Oxygen in FDA-approved Phototherapy. Chem. Sci. 2024. 15, 12431.
(8) Xu, Q.#, Zhang, Y.#, Zhu, M., Yan, C., Mao, W., Zhu, W., Guo, Z. Bent-to-Planar Si-Rhodamines: A Distinct Rehybridization Lights up NIR-II Fluorescence for Tracking Nitric Oxide in the Alzheimer's Disease Brain. Chem. Sci. 2023, 14, 4091.
(9) Zhang, L.#, Zhang, Y.#, Chi, W., Yan, C., Zhao, Z., Liu, X., Zhu, W.-H., Guo, Z. “Crossbreeding” Small-Molecular Weight NIR-II Flavchromenes Endows Activatable Multiplexed In Vivo Imaging. ACS Mater. Lett. 2022, 4, 1493.
授权专利：
(1)郭志前; 李娟; 张玉涛; 卢耀; 燕宸旭; 赵美玲; 赵袖妍; 朱为宏. 一种发光探针及其制备方法和应用: ZL202311076428.X. 2024-02-27.