刘尽尧
国家海外高层次人才引进青年项目获得者
研究员，博士生导师,
办公室：上海市浦东新区东方路1630号仁济医院17号楼1717室
邮箱：jyliu@sjtu.edu.cn
招生专业：应用化学（硕士）；制药工程（工硕）
工作经历
2013.4-2015.8 美国杜克大学，生物医学与工程系，博士后，合作导师：Ashutosh Chilkoti（美国发明院院士）
2015.9-2018.3 美国麻省理工学院，Koch肿瘤研究所，博士后，合作导师：Robert Langer（美国科学院、工程院、医学院三院院士）
2018.2-至今 上海交通大学医学院分子医学研究院，研究员，博士生导师
研究方向：
1. 新型生物医用高分子的可控制备
2. 药物传递系统的生物制备新技术
3. 智能仿生材料的生物合成新方法
4. 微生物改造与微生态调控新手段
l至今，以通讯作者在Matter、Nature Communications（5篇）、Science Advances（4篇）、Angew Chen Int Ed（2篇）、Advanced Materials（6篇）等期刊发表论文。
lJournal of Nanobiotechnology (Q1) 副主编
国家/省部级项目
1）国家重点研发计划课题，非天然碱基精准合成，2021.12-2026.9
2）国家自然科学基金委员会面上项目，胃内可停留给药系统的构建及应用研究，2019.1-2022.12
3) 上海市探索者计划，肠道菌群PET/CT示踪与监测技术研究，2021.12-2024.11
4）国家海外高层次人才引进青年项目D1410022（结题）
代表性论文
1. Lu Meng, Fengmin Yang, Yan Pang*, Zhenping Cao, Feng Wu, Deyue Yan*, Jinyao Liu*, Nanocapping-enabled charge reversal generates cell-enterable endosomal-escapable bacteriophages for intracellular pathogen inhibition. Science Advances, 2022, 8, eabq2005.
2. Juanjuan Li#, Qing Xia#, Haiyan Guo, Zhenzhen Fu, Yong Liu, Sisi Lin, Jinyao Liu*, Decorating bacteria with triple immune nanoactivators generates tumor-resident living immunotherapeutics. Angewandte Chemie International Edition, 2022, 61, e202202409.
3. Lu Wang#, Zhenping Cao#, Mengmeng Zhang, Sisi Lin, Jinyao Liu*, Spatiotemporally controllable distribution of combination therapeutics in solid tumors by dually modified bacteria. Advanced Materials, 2022, 34, 2106669.
4.Juanjuan Li#, Weiliang Hou#, Sisi Lin, Chao Pan, Lu Wang, Feng Wu, Jinyao Liu*, Polydopamine nanoparticle-mediated dopaminergic immunoregulation in colitis. Advanced Science, 2022, 9, 2104006.
5. Zhongmin Geng, Zhenping Cao, Rui Liu, Ke Liu, Jinyao Liu*, Weihong Tan, Aptamer-assisted tumor localization of bacteria for enhanced biotherapy. Nature Communications, 2021, 12, 6584.
6. Sisi Lin#, Subhajit Mukherjee#, Juanjuan Li, Weiliang Hou, Chao Pan, Jinyao Liu*, Mucosal immunity mediated modulation of the gut microbiome by oral delivery of probiotics into Peyer’s patches. Science Advances, 2021, 7, abf0677.
7. Chao Pan, Juanjuan Li, Weiliang Hou, Sisi Lin, Lu Wang, Yan Pang, Yufeng Wang, Jinyao Liu*, Polymerization-mediated multifunctionalization of living cells for enhanced cell-based therapy. Advanced Materials, 2021, 33, 2007379.
8. Shuang Li, Lu Wang, Yuting Gu, Lu Lin, Mengmeng Zhang, Min Jin, Chuanyuan Mao, Jun Zhou, Weiqi Zhang, Xiangang Huang, Claudia Corbo, Wei Tao*, Eryi Lu*, Jinyao Liu*, Biomimetic immunomodulation by crosstalk with nanoparticulate regulatory T cells. Matter, 2021, 4, 1.
9. Zhongmin Geng, Lu Wang, Ke Liu, Jinyao Liu*, Weihong Tan*, Enhancing anti-PD-1 immunotherapy by nanomicelles self-assembled from aptamer-multivalent-drug conjugates. Angewandte Chemie International Edition, 2021, 60, 15459.
10. Xinyue Wang, Zhenping Cao, Mengmeng Zhang, Lu Meng, Zunzhen Ming, Jinyao Liu*, Bioinspired oral delivery of gut microbiota by self-coating with biofilms. Science Advances 2020, 6, eabb1952.
11. Feng Wu, Yan Pang*, Jinyao Liu*, Swelling-strengthening hydrogels by embedding with deformable nanobarriers. Nature Communications 2020, 11, 4502.
12. Pingping Feng, Zhenping Cao, Xinyue Wang, Juanjuan Li, Jinyao Liu*, On-demand bacterial reactivation by restraining within a triggerable nanocoating. Advanced Materials 2020, 32, 2002406.
13. Zunzhen Ming, Yan Pang, Jinyao Liu*, Switching between elasticity and plasticity by network strength competition. Advanced Materials 2020, 32, 1906870.
14. Zhenping Cao#, Xinyue Wang#, Yan Pang, Shanshan Cheng, Jinyao Liu*, Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment. Nature Communications 2019, 10, 5783.
15. Zhenping Cao, Shanshan Cheng, Xinyue Wang, Yan Pang*, Jinyao Liu*, Camouflaging bacteria by wrapping with cell membranes. Nature Communications 2019, 10, 3452.