李星光，籍贯安徽安庆
特聘研究员，博导，中共党员
国家高层次青年人才
上海海外高层次人才
Email：lixingguang@ecust.edu.cn（报考请联系）
办公地址：华东理工大学徐汇校区实验三楼301室
招生专业
教育与工作经历
2011.09 – 2017.12 华东理工大学，化学与分子工程学院，理学博士，导师：刘培念教授
2015.09 – 2017.09 美国加州大学圣塔芭芭拉分校，化学与生物化学系，国家公派联培，导师：张立明教授
2018.03 – 2021.09 香港科技大学，化学系，博士后研究员，合作导师：孙建伟教授、唐本忠院士
2021.11 –至今 华东理工大学，化学与分子工程学院，特聘研究员、博士生导师
研究领域
功能有机分子设计及其在肿瘤诊疗中应用
生物医用分子/材料设计、合成及应用
催化不对称合成及药物活性分子开发
个人荣誉与获奖
国家高层次青年人才（2025）
“化学之星”（2023）
上海海外高层次人才（上海千人）（2021）
优秀博士毕业生（2018）
博士生国家奖学金（2015）
国家公派留学奖学金（2015）
发表论文
迄今在国际主流期刊发表论文37篇。以通讯或第一作者在Nature Catalysis、Nature Synthesis、Nature Communications (2篇)、Angew. Chem. Int. Ed. (4篇)、Science Advances、Advanced Materials (2篇)、Biomaterials、Small (2篇)、ACS Catalysis、CCS Chemistry等期刊发表论文30余篇。其中影响因子（IF）>10论文15篇。申请发明专利10项，授权2项。
主要成果如下：
1. X. Li*, X.-Z. Wang, B. Shen, Q.-Y. Chen, H. Xiang, P. Yu*, P.-N. Liu*
Organocatalyzed diastereo- and enantioselective synthesis of N–N atropisomeric isoindolinones bearing central chirality.
Nat. Commun. 2025, 16, 1662. (IF: 15.7)
2. X. Li, R. Yan, M. Tan, R. T. K. Kwok, J. Sun, H. Xiang*, X. Ma*, J. W. Y. Lam*, B. Z. Tang*
Facile Access to Piezoelectric Polyamides by Polyamidation of Carboxylic Acids and Ynamides for Potent Tumor Immunotherapy.
Angew. Chem. Int. Ed. 2025, 64, e202424923. (IF: 16.9)
3. H. Xu, X. Qiao, J. Liang, L. Qiu, L. Xue, Y. Fang, H. Xiang, X. Li*, Y. Chen*, H. Ding*
Organomolecular Ferroelectric Nanocatalyst Augments Tumor Immunotherapy by Inducing Apoptosis and Ferroptosis.
Adv. Mater. 2025, 37, 2417422. (IF: 26.8)
4. X. Li*, M.-L. Gao, S.-S. Wang, Y. Hu, D. Hou, P.-N. Liu*, H. Xiang*
Nanoscale covalent organic framework-mediated pyroelectrocatalytic activation of immunogenic cell death for potent immunotherapy.
Sci. Adv. 2024, 10, eadr5145. (IF: 12.5)
5. X. Li*, M.-L. Gao, S.-S. Wang, Y.-L. Li, T.-N. Liu, H. Xiang*, P.-N. Liu*,
Engineering an Organic Nanoplatform for Augmented Pyroeletroimmunotherapy.
Adv. Mater. 2024, 36, 2400756. (IF: 26.8)
6. C. You+, X. Li+(coauthor), D. Wang, H. Chen, L. Liang, Y. Chen*, Y. Zhao*, H. Xiang*
Self-Assembled Aza-Boron-Dipyrromethene for Ferroptosis-Boosted Sonodynamic Therapy.
Angew. Chem. Int. Ed. 2022, 61, e202210174. (IF: 16.9)
7. X. Li, Z. Li, J. Sun*
Quinone methides and indole imine methides as intermediates in enantioselective catalysis.
Nat. Synth. 2022, 1, 426–438. (IF: 20.0)
8. X. Li, M. Duan, P. Yu, K. N. Houk*, J. Sun*
Organocatalytic Enantioselective Dearomatization of Thiophenes by 1,10-Conjugate Addition of Indole Imine Methide.
Nat. Commun. 2021, 12, 4881. (IF: 15.7)
9. X. Li, M. Duan, Z. Deng, Q. Shao, M. Chen, G. Zhu*, K. N. Houk*, J. Sun*
Catalytic Enantioselective Synthesis of Chiral Tetraarylmethane
Nat. Catal. 2020, 3, 1010–1019. (IF: 37.8)
10. X. Li, J. Sun*
Enantioselective Synthesis of Chiral Allenes: Remote Asymmetric 1,8-Addition of Indole Imine Methide.
Angew. Chem. Int. Ed. 2020, 59, 17049–17054. (Hot paper, IF: 16.6)
11. X. Li, X. Ma, Z. Wang, P.-N. Liu*, L. Zhang*
Bifunctional Phosphine Ligand Enabled Gold-Catalyzed Alkynamide Cycloisomerization: Access to Electron-Rich 2-Aminofurans and Their Diels-Alder Adducts.
Angew. Chem. Int. Ed. 2019, 58, 17180–17184. (IF: 16.6)