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王琪



王琪(Qi Wang),博士,1985年生于四川。

华东理工大学-化学与分子工程学院

副教授,硕士生导师

办公室:徐汇校区实验13301Email: wangqi@ecust.edu.cn
硕士招生专业:应用化学

  

研究方向

生物荧光探针,致力于实现精准化个体诊疗方案。以多学科交叉为基础,将荧光探针作为切入点,将荧光生物探针与靶向药物载体有效结合,发展可用于疾病早期诊断,定点释放药物,并实时监测药物体内代谢的响应型荧光探针体系。已在Advanced Functional Materials, Biomaterials, Autophagy, Theranostics, Nanotoxicology等国际学术期刊上发表40余篇学术论文,总引用率达430次,其中第一作者文章16篇。获授权中国专利6项,申请美国专利2项。入选中国抗癌协会纳米肿瘤学专业委员会委员,中国抗癌协会会员

欢迎对应用化学、材料化学等研究方向感兴趣的研究生加入本课题组;同时欢迎应化、材料等专业本科生来课题组交流学习。

  

学习与工作经历

20049月—20086月,四川大学,药学院,本科

20089月—20146月,四川大学,药学院药剂专业,硕、博(导师:张志荣教授)

200126月—20146月,上海交通大学,肿瘤学,硕、博合培(导师:段友容教授)

20151月—20174月,新加坡南洋理工大学,博士后 (导师:Kathy Qian Luo教授)

20174月—20186月,华东理工大学,化学与分子工程学院,讲师

20186月—,华东理工大学,化学与分子工程学院,副教授(2018年获硕士导师资格)

  

科研项目

国家自然科学基金青年基金(项目负责人,在研)

中央高校基本科研业务费探索专项基金(项目负责人,在研)
国家自然科学基金面上项目(参与,在研)

华东理工大学高端诊断与精准治疗团队(参与)

  

  

代表性论著#为共同一作, *为通讯作者):

1.Qiang Li, Jun Cao, Qi Wang,* Jie Zhang, Shiqin Zhu, Zhiqian Guo, Wei-Hong Zhu.*Nanomized tumor-microenvironment active NIR fluorescent prodrug for ensuring synchronous occurrences of drug releasing and fluorescence tracing”. Journal of Materials Chemistry B. 2019, DOI: 10.1039/C8TB03188F

2.Qiang Li, Qi Wang#, Saibo Wang, Shiqin Zhu, Tianwen Yuan, Zhiqian Guo, Jun Cao,* He Tian, Wei-Hong Zhu. “Near-Infrared Fluorescent Theranostic Cisplatin Prodrug with Transcatheter Intra-Arterial Therapy: Application to Rabbit Hepatocellular Carcinoma”. Adv. Therap. 2018, 1800093.

3.Qi Wang, Xiangyu Zhang, Hongze Liao, Ying Sun, Li Ding, Yanwei Teng, Wei‐Hong Zhu*, Zhirong Zhang*, Yourong Duan*. “Multifunctional Shell–Core Nanoparticles for Treatment of Multidrug Resistance Hepatocellular Carcinoma” Advanced Functional Materials. 2018, 14, 1706124.

4.Ying Sun#, Qi Wang#, Jianhua Chen, Lei Liu, Li Ding, Ming Shen, Jin Li, Baoshan Han, Yourong Duan*. “Temperature-Sensitive Gold Nanoparticle-Coated Pluronic-PLL Nanoparticles for Drug Delivery and Chemo-Photothermal Therapy” Theranostics. 2017, 18, 4424-4444.

5.Qi Wang, Na Wei, Xiaofeng Liu, Alex Chang, Kathy Qian Luo*. “Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: a study of formulation optimization, toxicity, and pharmacokinetics” Oncotarget. 2017, 8, 12013- 12030.

6.Xiangyu Zhang#, Qi Wang#, Liubing Qin, Hao Fu, Yiwei Fang, Baoshan Han, Yourong Duan*. “EGF-modified mPEG-PLGA-PLL nanoparticle for delivering doxorubicin combined with Bcl-2 siRNA as a potential treatment strategy for lung cancer” Drug Delivery. 2016, 23, 2936-2945.

7.Qi Wang, Ying Sun, Zhirong Zhang*, Yourong Duan*.” Targeted polymeric therapeutic nanoparticles: Design and interactions with hepatocellular carcinoma” Biomaterials. 2015, 56, 229-40.

8.Qi Wang, Ming Shen, Tao Zhao, Yuanyuan Xu, Jiang Lin, Yourong Duan*, Hongchen Gu*. “Low toxicity and long circulation time of Polyampholyte-coated magnetic nanoparticles for blood pool contrast agents” Scientific reports. 2015, 5, 7774.

9.Qi Wang, Peifeng Liu, Ying Sun, Zelai He, Tao Gong, Xun Sun, Zhirong Zhang*, Yourong Duan*. “Preparation and properties of biocompatible PS-PEG/Calcium phosphate nanospheres” Nanotoxicology. 2014, 9, 190-200.

10.Qi Wang, Tao Gong, Xun Sun, Zhirong Zhang*. “Uptake mechanism and endosomal fate of drug- phospholipid lipid nanoparticles in subcutaneous and in situ hepatoma.” Journal of Biomedical Nanotechnology. 2014, 10, 993-1003.

11.Qi Wang, Yourong Duan. “Study of SiRNA-loaded PS-mPEG/CaP nanospheres on lung cancer.” Journal of Nanoparticle Research. 2014, 16, 2421.

12.Qi Wang, Pei Liu, Peifeng Liu, Tao Gong, Suming Li, Yourong Duan*, Zhirong Zhan*g. “Preparation, blood coagulation and cell compatibility evaluation of chitosan-graft-polylactide copolymers.” Biomedical Materials. 2014, 9, 015007.

13.Qi Wang, Peifeng Liu, Ying Sun, Heng Wu, Xiaoyu Li,Yourong Duan*, and Zhirong Zhang*. “Pluronic-Poly[-(4-aminobutyl)-l-glycolic acid] Polymeric Micelle-Like Nanoparticles as Carrier for Drug Delivery.” Journal of Nanoscience and Nanotechnology. 2013, 13, 1-8.

14.Qi Wang, Tao Gong, Xun Sun, Zhirong Zhang*. “Structural characterization of novel phospholipids lipid nanoparticles for controlled drug delivery.” Colloid Surface:B. 2011, 84, 406-12.

15.Qi Wang, Shuoyang Li, Peifeng Liu, Ming Shen, Tao Gong, Yourong Duan*, Zhang Zhi-Rong*. “HPLC evaluation on 3-n-butylphthalide distribution.” Journal of Applied Pharmaceutical Science. 2012, 2, 016-020.

16.Qi Wang, Yourong Duan. World Clinical Drugs. 2010, 31(8), 469-473.

17.Qi Wang, Yourong Duan. World Clinical Drugs. 2009, 30(11), 666-669.

18.Qi Wang, Mingjie Zhu. China Oncology. 2008, 18(9), 681-684.

19.Li Ding, Qi Wang, Ming Shen, Ying Sun, Xiangyu Zhang, Can Huang, Jianhua Chen, Rongxin Li, Yourong Duan. Autophagy. 2017, 7:1176-1190.

20.Peifeng Liu, Liubin Qin, Qi Wang, Ying Sun, Mingjie Zhu, Ming Shen, Yourong Duan. Biomaterials. 2012, 33: 6739.

21.Peifeng Liu, Hongbin Wang, Qi Wang, Ying Sun, Zhiyong Wan, Yourong Duan. Journal of Nanoscience and Nanotechnology. 2012, 12: 1.

22.Peifeng Liu, Yanming Sun, Qi Wang, Ying Sun, He Li, Yourong Duan. Biomaterials. 2014, 5: 760-770.

23.Yunfei Wang, Peifeng Liu, Yourong Duan, Xia Yin, Qi Wang, Xiaofei Liu,Xinran Wang, Jinhua Zhou, Wenwen Wang, Lihua Qiu, Wen Di. Biomaterials. 2014, 35: 983-992.

24.Zelai He, Qi Wang, Ying Sun, Ming Shen, Mingjie Zhu, Malin Gu, Yi Wang and Yourong Duan. Polymer Edition. 2014, 25: 943-964.

25.Liubin Qin, Ying Sun, Peifeng Liu, Qi Wang, Baosan Han and Yourong Duan. Polymer Edition. 2013, 24(15): 1757-1766.

26.Zelai He, Ying Sun, Qi Wang, Ming Shen, Mingjie Zhu, Fengqian Li*, and YourongDuan*. Degradation and bio-safety evaluation of mPEG-PLGA-PLL copolymer-prepared nanoparticles. The Journal of Physical Chemistry C. 2015, 119, 3348-3362.

  

专利

1.朱英杰,王可伟,段友容,孙颖,王琪。 磷酸钙/嵌段共聚物复合多孔纳米球及其制备方法,ZL 2009 1 0055356.4,发明专利。

2.段友容,孙颖,刘培峰,于晖,亓雪莲,王琪,陈晓炎,李晓昱。 聚乙二醇-聚乳酸羟基乙酸-聚赖氨酸纳米递送系统、制备方法及其应用,ZL 2009 1 0247576.7,发明专利。

3.王琪,袁佩忠。一种食用真菌的组合物和应用,200810204666.3,发明专利。

4.梁晓飞,段友容,王琪,李晓昱,孙彦明。靶向性季铵盐类阳离子高分子脂质基因载体、制备方法及应用,201010153815.5,发明专利。

5.朱英杰,王可伟,段友容王琪。磷酸钙纳米结构空心微球及其制备方法,200910198813.5,发明专利。

  

网页发布时间: 2019-01-23 16:31