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陈宜峰

陈宜峰

博士,教授,博士生导师,入选“中组部第十三批千人计划青年项目”

地址:上海市徐汇区梅陇路130号华东理工大学化学与分子工程学院实验三楼435室

邮件地址: yifengchen@ecust.edu.cn


教育及工作经历:

07/2017-:       教授,华东理工大学化学与分子工程学院

02/2014-06/2017:  博士后, 耶鲁大学化学系,合作导师: Timothy R. Newhouse教授

02/2013-01/2014:  博士后, 麻省理工学院化学系,合作导师: Stephen L. Buchwald教授

07/2012-01/2013:  研究助理, 中国科学院上海有机化学研究所,导师: 刘元红研究员

09/2007-06/2012:  博士,中国科学院上海有机化学研究所,导师: 刘元红研究员

09/2003-07/2007:  本科,苏州大学化学化工学院,导师: 邹建平教授


获奖及荣誉:

2017:      第十三批国家千人计划青年项目 

2015-2016:   耶鲁大学Anderson博士后奖学金

2012:      中国科学院院长奖学金优秀奖 

2012:      上海市优秀毕业生


研究方向:

陈宜峰博士的研究方向主要是利用过渡金属催化的手段解决有机合成化学中长期存在的挑战性课题,设计合成新型催化剂,发展高活性、实用的有机合成方法学,同时通过对反应机理的研究,为新型反应设计提供指导意义,最终实现具有生理活性的天然产物全合成以及药物分子合成的应用。 


热忱欢迎对有机合成、金属有机化学和天然产物全合成等研究方向感兴的硕士生、博士生和博士后加入本课题组,同时欢迎本科生来课题组交流学习。


代表著作:

1. Chen, Y.; Huang, D.; Zhao, Y.; Newhouse, T. R.* Allyl-Palladium Catalyzed Ketone Dehydrogenation Enables Telescoping with Enone α,β-Vicinal Difunctionalization. Angew. Chem. Int. Ed. 2017, 56, 8258.


2. Chen, Y.; Turlik, A.; Newhouse, T. R.* Amide α,β-Dehydrogenation Using Allyl-Palladium Catalysis and a Hindered Monodentate Anilide. J. Am. Chem. Soc. 2016, 138, 1166. 


3. Chen, Y.; Romaire, J. P.; Newhouse, T. R.* Palladium-Catalyzed α,β-Dehydrogenation of Esters and Nitriles. J. Am. Chem. Soc. 2015, 137, 5875. 


4. Chen, Y.; Chen, M.; Liu, Y.* Gold-Catalyzed Cyclization of 1,6-Diyne-4-en-3-ols: Stannyl Transfer from 2-Tributylstannylfuran Through Au/Sn Transmetalation. Angew. Chem. Int. Ed. 2012, 51, 6181. 


5. Chen, Y.; Chen, M.; Liu, Y.* Gold-Catalyzed Cascade Cyclizations of 1,6-Diynyl Carbonates to Benzo[b]fluorenes Involving Hydroarylation of Oxocarbenium Ion Intermediates and Decarboxylative Etherification. Angew. Chem. Int. Ed. 2012, 51, 6493. 


6. Chen, M.; Chen, Y.; Sun, N.; Zhao, J. Liu, Y.*; Li, Y.* Gold-Catalyzed Oxidative Ring Expansion of 2-Alkynyl-1,2-Dihydropyridine or -quinolines: Highly Efficient Synthesis of Functionalized Azepine or Benzazepine Scaffolds. Angew. Chem. Int. Ed. 2015, 54, 1200.


7. Chen, Y.; Wang, L.; Sun, N.; Xie, X.; Zhou, X.; Chen, H.; Li, Y.*; Liu, Y.* Gold(I)-Catalyzed Furan-yne Cyclizations Involving 1,2-Rearrangement: Efficient Synthesis of Functionalized 1-Naphthols and Its Application to the Synthesis of Wailupemycin G. Chem. Eur. J. 2014, 20, 12015.


8. Chen, Y.; Wang, L.; Li, Y.*; Liu, Y.* Grignard Reagent Acceleration of the Intramolecular Diels-Alder Reaction of Furans with Unactivated Alkynes: Toward Structurally Complex Oxabicyclic Alkene. Chem. Eur. J. 2011, 17, 12582.


9. Chen, Y.; Li, G.; Liu, Y.* Gold-Catalyzed Cascade Friedel-Crafts/Furan-Yne Cyclization/Heteroenyne Metathesis for the Highly Efficient Construction of Phenanthrene Derivatives. Adv. Syn. Catal. 2011, 353, 392.


10. Chen, Y.; Liu, Y.* A New Gold-Catalyzed Approach to Multisubstituted Fulvenes via Cycloisomerization of Furan/Ynes. J. Org. Chem. 2011, 76, 5274. 


11. Chen, Y.; Lu, Y.; Li, G.; Liu, Y.* Gold-catalyzed Cascade Friedel-Crafts/Furan-Alkyne Cycloisomerizations for the Highly Efficient Synthesis of Arylated (Z)-Enones or –Enals. Org. Lett. 2009, 11, 3838.


12. Turlik, A.; Chen, Y.; Newhouse, T. R.* Dehydrogenation Adjacent to Carbonyls Using Palladium–Allyl Intermediates. Synlett 2016, 27, 331. 



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