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李大伟


李大伟，教授，博士生导师

 

联系地址：第五教学楼203室；联系电话：021-64252372

Email: daweili@ecust.edu.cn

 

研究方向：生物分析，环境检测

  

招生专业

博士研究生招生专业：分析化学

硕士研究生招生专业：分析化学

工程博士研究生招生专业：制药工程（化学）

工程硕士研究生招生专业：生物与医药

  

教育及工作简历

1996/09-2000/07，郑州大学，学士；

2000/08-2002/08，本溪钢铁集团有限公司，工程师；

2002/09-2008/10，大连理工大学，博士（硕博连读）；

2008/12-2011/02，华东理工大学，博士后；

2015/03-2016/03，密歇根大学，访问学者；

2011/03-至今， 华东理工大学，化学与分子工程学院，讲师、副教授、教授

  

主要学术成绩

上海市浦江人才计划入选者（2017年度）。以表面增强拉曼散射为基础，开展环境检测与生物分析新材料、新方法、新技术与新器件等研究。在Angew. Chem. Int. Ed.、Anal. Chem.等国际著名学术期刊上发表第一或通讯作者SCI论文60余篇，发表文章近5年被SCI刊物他引3000余次；授权发明专利5项，PCT专利1项；获中国分析测试协会科学技术奖特等奖1项（第三完成人）。

  

代表性成果

1. 论文

  1. L. Jiang, C. H. He, H. Y. Chen, C. Y. Xi, E. K. Fodjo, Z. R. Zhou, R. C. Qian, D. W. Li*, M. E. Hafez, In situ monitoring of hydrogen peroxide released from living cells using a ZIF-8-based surface-enhanced Raman scattering sensor, Anal. Chem., 2021, 93, 12609-12616. (IF=6.986)

  2. B. B. Chen, S. Chang, J. Lv, R. C. Qian*, D. W. Li*, Temperature-modulated porous gadolinium micro-networks with hyperchrome-enhanced fluorescence effect, Chem. Eng. J., 2021, 422, 129959. (IF=13.273)

  3. Y. T. Gao, B. B. Chen, L. Jiang, J. Lv, S. Chang, Y. Wang, R. C. Qian, D. W. Li*, M. E. Hafez, Dual-emitting carbonized polymer dots synthesized at room temperature for ratiometric fluorescence sensing of vitamin B12, ACS Appl. Mater. Interfaces, 2021, 13, 50228-50235. (IF=9.229)

  4. L. Jiang, L. Wang, D. S. Zhan, W. R. Jiang, E. K. Fodjo, M. E. Hafez, Y. M. Zhang, H. Zhao, R. C. Qian, D. W. Li*, Electrochemically renewable SERS sensor: A new platform for the detection of metabolites involved in peroxide production, Biosens. Bioelectron., 2021, 175, 112918. (IF=10.618)

  5. L. Wang, Z. F. Gan, D. Guo, H. L. Xia, F. T. Patrice, M. E. Hafez, D. W. Li*, Electrochemistry-regulated recyclable SERS sensor for sensitive and selective detection of tyrosinase activity, Anal. Chem., 2019, 91, 6507-6513. (IF=6.986)

  6. H. Y. Chen, E. K. Fodjo, L. Jiang, S. Chang, J. B. Li, D. S. Zhan, H. X. Gu, D. W. Li*, Simultaneous detection of intracellular nitric oxide and peroxynitrite by a surface-enhanced Raman scattering nanosensor with dual reactivity, ACS Sens., 2019, 4, 3234-3239. (IF=7.711)

  7. D. Li, Y. Ma, H. Duan, W. Deng*, D. W. Li*, Griess reaction-based paper strip for colorimetric/fluorescent/SERS triple sensing of nitrite, Biosens. Bioelectron., 2018, 99, 389-398. (IF=10.618)

  8. D. W. Li*, H. Y. Chen, Z. F. Gan, J. J. Sun, D. Guo, L. L. Qu, Surface-enhanced Raman scattering nanoprobes for the simultaneous detection of endogenous hypochlorous acid and peroxynitrite in living cells, Sensors & Actuators: B Chemical, 2018, 277, 8-13. (IF=7.460)

  9. J. Cui, K. Hu, J. J. Sun, L. L. Qu, D. W. Li*, SERS nanoprobes for the monitoring of endogenous nitric oxide in living cells, Biosens. Bioelectron., 2016, 85, 324-330. (IF=10.618)

  10. D. W. Li*, L. L. Qu, K. Hu, Y. T. Long*, H. Tian, Monitoring of endogenous hydrogen sulfide in living cells using surface-enhanced Raman spectroscopy, Angew. Chem. Int. Ed., 2015, 127, 12949-12952. (IF=15.336)

  11. Y. Cao, D. W. Li*, X. Y. Liu, L. J. Zhao, Y. T. Long*, Highly selective detection of carbon monoxide in living cells by palladacycle carbonylation-based SERS nanosensors, Anal. Chem., 2015, 87, 9696-9701. (IF=6.986)

  12. L. L. Qu, D. W. Li*, L. X. Qin, J. Mu, J. S. Fossey, Y. T. Long, Selective and sensitive detection of intracellular O2•- using Au NPs cytochrome c as SERS nanosensors, Anal. Chem., 2013, 85, 9549-9555. (IF=6.986)

  13. Y. T. Li, L. L. Qu, D. W. Li*, Q. X. Song, Y. T. Long*, Rapid and sensitive in-situ detection of polar antibiotics in water using a disposable Ag-graphene sensor based on electrophoretic preconcentration and surface-enhanced Raman spectroscopy, Biosens. Bioelectron., 2013, 43, 94-100. (IF=10.618)

  14. L. L. Qu, D. W. Li*, J. Q. Xue, W. L. Zhai, J. S. Fossey, Y T. Long*, Batch fabrication of disposable screen-printed SERS arrays, Lab Chip, 2012, 12, 876- 881. (IF=6.799, 封面文章)

  15. D. W. Li, L. L. Qu, J. Q. Xue, W. L. Zhai, J. S. Fossey, Y. T. Long*, Facile on-site detection of substituted aromatic pollutants in water using thin layer chromatography combined with surface-enhanced Raman spectroscopy, Environ. Sci. Technol., 2011, 45, 4046-4052. (IF=9.028) 

2. 专利

1) 李大伟、龙亿涛、渠陆陆、李原婷、薛进群、宋奇侠，高重复性表面增强拉曼光谱活性基底的制备方法，授权时间：2014.4，中国，专利号：ZL 201110355896.1。

2) Yitao Long, Dawei Li, Lulu Qu, Wenlei Zhai, Jinqun Xue, Wei Song. Metallic Nanoparticles and Methods for Their Preparation and Use. WO 2013040782A1. 2013.03.28。

3) 龙亿涛、李大伟、李萌、宋伟、李原婷、李扬，重金属离子现场快速检测方法，授权时间：2011.6，中国，专利号：ZL 201010159083.0。

4)龙亿涛、李大伟、渠陆陆、翟文磊、李扬、梁杰，水污染事件中有机污染物现场应急检测技术，授权时间：2012.6，中国，专利号：ZL 201010022954.4。
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