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华鑫




华鑫 特聘副研究员,硕士生导师

出生年月:198811

Email: xinhua@ecust.edu.cn

联系地址:上海市徐汇区梅陇路130号实验三楼101

  

招生专业:分析化学

  

主要学习与工作经历:

2018.03-至今,华东理工大学,特聘副研究员

2016.01-2018.02,华东理工大学,博士后,合作导师:龙亿涛 教授

2010.09-2015.12,东南大学,博士,专业:应用化学,导师:刘松琴 教授

2013.04-2015.04,美国Pacific Northwest National Laboratory,联合培养,导师:Dr. Xiao-Ying Yu

2006.09-2010.06,东南大学,本科,专业:化学工程与工艺,导师:刘松琴 教授


研究方向:

1 基于飞行时间二次离子质谱成像的原位单细胞、疾病组织分析

2 原位质谱-电化学联用研究电极-电解质界面、光电界面动态变化

  

近五年来,利用飞行时间-二次离子质谱开展了电极-电解质界面,钙钛矿太阳能电池光电界面以及生物界面的研究工作,成功实现真空下固液界面的原位实时质谱检测,为研究能源、生物动态界面过程提供了重要依据。利用高分辨质谱成像研究单细胞与药物、环境相互作用机制。通过对大气颗粒物成分进行层层解析,研究颗粒物形成过程。研究成果发表在Anal. Chem., Chem. Comm.等重要SCI期刊上,主持包括国家自然科学基金青年基金,上海市科委“扬帆计划”,上海市自然科学面上基金等在内的多个科研项目。

  

代表性论文:

1.J.-G. Wang; X. Hua*; H.-L. Xia; Y.-T. Long*, Pore Confined Liquid-Vacuum Interface for Charge Transfer Study in Electrochemical Process, Analytical Chemistry, 2019, accepted, doi: 10.1021/acs.analchem.8b05051.

2.X. Hua; H.-W. Li; Y.-T. Long*, Investigation of silver nanoparticle induced lipids changes on single cell surface by ToF-SIMS, Analytical Chemistry, 2018, 90, 1072–1076

3.D. Xu; X. Hua*; S.-C. Liu; H.-W. Qiao; H.-G. Yang; Y.-T. Long*; H. Tian, In situ and real-time ToF-SIMS analysis of light-induced chemical changes in perovskite CH3NH3PbI3, Chemical Communications, 2018, 54, 5434-5437.

4.X. Hua; L-J. Zhao; Y.-T. Long*, Investigation of the Ionization Mechanism of NAD+/ NADH-Modified Gold Electrodes in ToF-SIMS Analysis, Journal of The American Society for Mass Spectrometry, 2018, 29, 1567-1570.

5.J. Lu; X. Hua*; Y.-T. Long, Recent advances in real-time and in situ analysis of an electrode–electrolyte interface by mass spectrometry, Analyst,2017, 142, 691-699.

6.D. Huang; X. Hua*; G.-L. Xiu*; Y.-J. Zheng; X.-Y. Yu*; Y.-T. Long, Secondary ion mass spectrometry: The application in the analysis of atmospheric particulate matter, Analytica Chimica Acta,2017, 989, 1-14.

7.X. Hua; C. Szymanski; Z. Wang; Y. Zhou; X. Ma; J. Yu; J. Evans; G. Orr; S. Liu*; Z. Zhu*, X.-Y. Yu*, Chemical imaging of molecular changes in a hydrated single cell by dynamic secondary ion mass spectrometry and super-resolution microscopy, Integrative Biology2016, 8, 635-644.

8.X. Hua; M. J. Marshall; Y. Xiong; X. Ma; Y. Zhou; A. E. Tucker; Z. Zhu; S. Liu*; X.-Y. Yu*, Two-dimensional and three-dimensional dynamic imaging of live biofilms in a microchannel by time-of-flight secondary ion mass spectrometry, Biomicrofluidics,2015, 9, 031101.

9.X. Hua; X.-Y. Yu*; Z. Wang; L. Yang; B. Liu; Z. Zhu; A. E. Tucker; W. B. Chrisler; E. A. Hill; T. Thevuthasan, Y. Lin, S. Liu, M. Marshall*, In situ molecular imaging of a hydrated biofilm in a microfluidic reactor by ToF-SIMS, Analyst,2014, 139, 1609-1613.

10.X. Hua; Z. Zhou; L. Yuan; S. Liu*, Selective collection and detection of MCF-7 breast cancer cells using aptamer-functionalized magnetic beads and quantum dots based nano-bio-probes, Analytica Chimica Acta,2013, 788, 135-140.


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