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李星光



李星光  

 

特聘研究员,博导,中共党员

籍贯:安徽安庆,电子邮箱:lixingguang@ecust.edu.cn;

地址:上海市徐汇区梅陇路130号,华东理工大学,实验3301    

教育及工作经历

2021.11-至今     华东理工大学化分学院 特聘研究员,博导(上海市海外高层次人才引进) 

2020.09-2021.09  香港科技大学  化学系   博士后研究员  合作导师:Benzhong Tang (唐本) 院士

2018.03-2020.08  香港科技大学  化学系   博士后研究员  合作导师:Jianwei Sun (建伟) 教授

2015.09-2017.09  美国加州大学圣塔芭芭拉分校-化学与生物化学系 联合培养博士 导师:Liming Zhang教授

2011.09-2017.12  华东理工大学化分学院  博士         导师:刘培念教授

研究领域

² 有机合成:不对称催化,过渡金属催化

² 功能性发光有机分子和聚合物的设计合成及性质研究

 

博士、硕士研究生招生专业:有机化学

工程硕士招生专业:制药工程

主要学术成绩

申请人长期从事有机小分子和聚合物高分子的催化合成方法开发及其生物学应用的研究,在有机合成和高分子合成方面积累了丰富的经验,并取得了一系列重要研究成果:首次实现高效催化合成手性四芳基甲烷,并研究其的抗肿瘤和抗病毒活性;实现活性二烯、手性联烯和多类手性杂环的催化合成。同时,揭示和发展了有机以及过渡金属催化体系的多功能活化模式。目前已发表SCI论文17篇,其中以第一作者Nature Catalysis (IF: 41.813), Nature SynthesisNature Communications (IF: 14.919), Angew. Chem. Int. Ed. (IF: 15.3362)等国际主流期刊发表SCI论文12篇。所发表SCI论文被引400。申请发明专利3项,授权1项。相关成果得到了国际同行的广泛关注和高度评价。代表性论文如下:

 

1. Xingguang Li, Meng Duan, Zhiqin Deng, Qianzhen Shao, Min Chen, Guangyu Zhu*, Kendall N. Houk*, Jianwei Sun*, Catalytic enantioselective synthesis of chiral tetraarylmethane, Nat. Catal., 2020, 3, 10101019. (IF: 41.813)

2. Xingguang Li, Zhiyang Li, Jianwei Sun*, Quinone methides and indole imine methides as intermediates in enantioselective catalysis, Nat. Synth., 2022, 1, https://doi.org/10.1038/s44160-022-00072-x.

3. Xingguang Li, Meng Duan, Peiyuan Yu, Kendall N. Houk*, Jianwei Sun* Organocatalytic enantioselective dearomatization of thiophenes by 1,10-conjugate addition of indole imine methide, Nat. Commun., 2021, 12, 4881. (IF: 14.919)

4. Xingguang Li, Jianwei Sun*, Enantioselective Synthesis of Chiral Allenes: Remote Asymmetric 1,8-Addition of Indole Imine Methide, Angew. Chem. Int. Ed. 2020, 59, 17049–17054. (Hot paper). (IF: 15.336)

5. Xingguang Li, Xu Ma, Zhixun Wang, Pei-Nian Liu*, Liming Zhang*, Bifunctional Phosphine Ligand Enabled Gold-Catalyzed Alkynamide Cycloisomerization: Access to Electron-Rich 2-Aminofurans and Their Diels-Alder Adducts, Angew. Chem. Int. Ed. 2019, 58, 17180–17184. (IF: 15.336)

6. Xingguang Li, Jianwei Sun*, “Asymmetric dearomatization enabled by chiral Brønsted acid activation of ynamides” Sci. China: Chem., 2022, 65, 34 (IF: 9.445)

7. Xingguang Li, Zhixun Wang, Xu Ma, Pei-Nian Liu*, Liming Zhang*, Designed Bifunctional Phosphine Ligand-Enabled Gold-Catalyzed Isomerizations of Ynamides and Allenamides: Stereoselective and Regioselective Formation of 1-Amido-1,3-Dienes, Org. Lett. 2017, 19, 5744–5747. (IF: 6.091)

8. Xing Guang Li, Min Sun, Qiao Jin, Kai Liu, Pei Nian Liu*, Access to Isoquinolines and Isoquinolin-3-ols via Rh(III)-Catalyzed Coupling/Cyclization Cascade Reaction of Arylimidates and Diazo Compounds. J. Org. Chem., 2016, 81, 39013910. (IF: 4.335)

9. Xing Guang Li, Min Sun, Kai Liu, Qiao Jin, Pei Nian Liu*, Rh(III)-catalyzed C-H activation/cyclization of benzamides and diazo compounds to form isocoumarins and α-pyrones. Chem. Commun., 2015, 51, 23802383. (ESI highly cited paper & Highlighted by ChemInform in 2016) (IF: 5.996)

10. Xing Guang Li, Min Sun, Kai Liu, Pei Nian Liu*, Oxidative Alkenylation/Annulation of Benzimidates via Ruthenium(II)-catalyzed C-H Activation to Generate 3-Methyleneisoindolin-1-ones. Adv. Syn. Catal., 2015, 357, 395399. (IF: 5.851)

11. Xing Guang Li, Kai Liu, Gang Zou, Pei Nian Liu*, Rhodium (III)-Catalyzed, C-H Activated Annulation to Form Isocoumarins and α-Pyrones using the O-N Bond as an Internal Oxidant. Adv. Syn. Catal., 2014, 356, 1496-1500. (Inside Cover Article) (IF: 5.851)

12. Xing Guang Li, Kai Liu, Gang Zou, Pei Nian Liu*, Ruthenium-Catalyzed Alkenylation of Arenes with Alkynes or Alkenes by 1,2,3-Triazole- Directed C-H Activation. Eur. J. Org. Chem., 2014, 78787888.

 

个人荣誉与获奖

² 上海市海外高层次人才引进计划(2021)

² 华东理工大学优秀毕业生(2018)

² 教育部全国优秀博士生奖学金(2015)

² 华东理工大学“优秀学生”奖 (2015)

² 国家留学基金委公派留学生奖学金 (2015)

 


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